Published in
Royal Society of Chemistry, Catalysis Science & Technology, 13(11), p. 4491-4499, 2021
DOI: 10.1039/d1cy00609f
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Chemogenetic engineering of nitrobindin toward an artificial epoxygenase
Journal article published in 2021 by
Daniel F. Sauer 
,
Malte Wittwer,
Ulrich Markel ,
Alexander Minges ,
Markus Spiertz,
Johannes Schiffels ,
Mehdi D. Davari ,
Georg Groth ,
Jun Okuda ,
Ulrich Schwaneberg
,
Malte Wittwer,
Ulrich Markel ,
Alexander Minges ,
Markus Spiertz,
Johannes Schiffels ,
Mehdi D. Davari ,
Georg Groth ,
Jun Okuda ,
Ulrich Schwaneberg
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Abstract
Chemogenetic engineering turned the heme protein nitrobindin into an artificial epoxygenase: MnPPIX was introduced and subsequent protein engineering increased the activity in the epoxidation of styrene derivatives by overall 7-fold.