Published in

Royal Society of Chemistry, RSC Medicinal Chemistry, 4(12), p. 448-471, 2021

DOI: 10.1039/d0md00370k

Links

Tools

Export citation

Search in Google Scholar

Put a ring on it: application of small aliphatic rings in medicinal chemistry

Journal article published in 2021 by Matthias R. Bauer, Paolo Di Fruscia, Simon C. C. Lucas ORCID, Iacovos N. Michaelides ORCID, Jennifer E. Nelson ORCID, R. Ian Storer, Benjamin C. Whitehurst ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Aliphatic small rings including cyclopropanes, cyclobutanes, oxetanes, azetidines and bicyclo[1.1.1]pentanes have been increasingly exploited in medicinal chemistry. This review summarises judicious successful application and reported limitations of these ring systems.