Published in
Royal Society of Chemistry, Chemical Communications, 12(57), p. 1450-1453, 2021
DOI: 10.1039/d0cc08135c
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Ion mobility-mass spectrometry shows stepwise protein unfolding under alkaline conditions
Journal article published in 2021 by
Cagla Sahin 
,
Nicklas Österlund ,
Axel Leppert ,
Janne Johansson,
Erik G. Marklund ,
Justin L. P. Benesch,
Leopold Luna Ilag,
Timothy M. Allison ,
MIchael Landreh
,
Nicklas Österlund ,
Axel Leppert ,
Janne Johansson,
Erik G. Marklund ,
Justin L. P. Benesch,
Leopold Luna Ilag,
Timothy M. Allison ,
MIchael Landreh
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Abstract
Although native mass spectrometry is widely applied to monitor chemical or thermal protein denaturation, it is not clear to what extent it can inform about alkali-induced unfolding.