Published in
Royal Society of Chemistry, Lab on a Chip, 2(21), p. 365-377, 2021
DOI: 10.1039/d0lc00672f
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Developing an advanced gut on chip model enabling the study of epithelial cell/fibroblast interactions
Journal article published in 2021 by
Marine Verhulsel,
Anthony Simon,
Moencopi Bernheim-Dennery,
Venkata Ram Gannavarapu,
Lauriane Gérémie,
Davide Ferraro 
,
Denis Krndija,
Laurence Talini ,
Jean-Louis Viovy,
Danijela Matic Vignjevic,
Stéphanie Descroix
,
Denis Krndija,
Laurence Talini ,
Jean-Louis Viovy,
Danijela Matic Vignjevic,
Stéphanie Descroix
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Abstract
We report on a new gut on chip combining the co-culture of primary epithelial and stromal cells in 3D biomimetic scaffold. Proper segregation of dividing and differentiated cells along the crypt-villus axis was achieved in these unique conditions.