Published in
Royal Society of Chemistry, Food and Function, 2(12), p. 656-667, 2021
DOI: 10.1039/d0fo02286a
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The role of microRNA-33 as a key regulator in hepatic lipogenesis signaling and a potential serological biomarker for NAFLD with excessive dietary fructose consumption in C57BL/6N mice
Journal article published in 2021 by
Jeong Hoon Pan,
Hanvit Cha,
Jingsi Tang,
Seoyoon Lee,
Suk Hee Lee,
Brandy Le,
Mersady C. Redding,
Sangyub Kim,
Mona Batish 
,
Byungwhi C. Kong,
Jin Hyup Lee,
Jae Kyeom Kim
,
Byungwhi C. Kong,
Jin Hyup Lee,
Jae Kyeom Kim
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Abstract
Fructose-induced hepatic miR-33 suppression lead to fatty liver via upregulation of SREBP1. Additionally, fructose-induced hepatic ferroptosis may cause a spill-over of miR-33 into blood stream, which could be a potential serological biomarker for fructose-induced NAFLD.