Published in
Royal Society of Chemistry, Dalton Transactions, 1(50), p. 323-335, 2021
DOI: 10.1039/d0dt03490h
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A Novel Ruthenium(II) Gallic Acid Complex Disrupts the Actin Cytoskeleton and Inhibits Migration, Invasion and Adhesion of Triple Negative Breast Tumor Cells
Journal article published in 2020 by
Angélica E. Graminha 
,
João Honorato ,
Rodrigo S. Correa,
Marcia Regina Cominetti ,
Antonio Carlos S. Menezes ,
Alzir A. Batista
,
João Honorato ,
Rodrigo S. Correa,
Marcia Regina Cominetti ,
Antonio Carlos S. Menezes ,
Alzir A. Batista
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Abstract
Ru(ii) complexes with gallic acid and derivatives interact with biomolecules and show high SI among non-tumor/tumor breast cells. The gallic acid complex causes damage to the cell cytoskeleton inhibiting adhesion, invasion, and migration of tumor cells.