Published in
Royal Society of Chemistry, Dalton Transactions, 1(50), p. 362-375, 2021
DOI: 10.1039/d0dt03194a
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Design, synthesis and biological evaluation of dihydro-2-quinolone platinum(IV) hybrids as antitumor agents displaying mitochondria injury and DNA damage mechanism
Journal article published in 2020 by
Zhifang Liu,
Zuojie Li,
Tao Du,
Yan Chen,
Qing-Peng Wang 
,
Guoshuai Li,
Min Liu ,
Ning Zhang ,
DaCheng Li,
Jun Han
,
Guoshuai Li,
Min Liu ,
Ning Zhang ,
DaCheng Li,
Jun Han
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Abstract
Dihydro-2-quinolone platinum(iv) hybrids exhibit effective antitumor activities by causing serious mitochondria injury and DNA damage, and show great potential in reversing cisplatin resistance and improving antitumor efficacies.