Royal Society of Chemistry, Organic and Biomolecular Chemistry, 1(19), p. 220-232, 2021
DOI: 10.1039/d0ob01997f
Full text: Unavailable
Highly potent anti-HBV lipopeptides were prepared by S-lipidation using the “Cysteine Lipidation on a Peptide or Amino Acid” (CLipPA) thiol–ene reaction. Interestingly, target binding efficacy correlated poorly with inhibitory potency.