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Royal Society of Chemistry, Inorganic Chemistry Frontiers, 1(8), p. 141-155, 2021

DOI: 10.1039/c9qi01704f

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Novel organo-osmium(ii) proteosynthesis inhibitors active against human ovarian cancer cells reduce gonad tumor growth inCaenorhabditis elegans

Journal article published in 2021 by Enrique Ortega ORCID, Francisco J. Ballester ORCID, Alba Hernández-García ORCID, Samanta Hernández-García ORCID, M. Alejandra Guerrero-Rubio, Delia Bautista, M. Dolores Santana ORCID, Fernando Gandía-Herrero, José Ruiz ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Novel Os(ii) arene complexes with a deprotonated ppy or ppy-CHO C^N ligand have been synthesized to selectively act on cancer cells as proteosynthesis inhibitorsin vitroand exert antitumor activityin vivoinC. elegansmodels.