Published in
Royal Society of Chemistry, New Journal of Chemistry, 46(44), p. 20013-20020, 2020
DOI: 10.1039/d0nj03425h
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Synthetic copolymer conjugates of docetaxel andin vitroassessment of anticancer efficacy
Journal article published in 2020 by
Cameron W. Evans 
,
Sky Edwards ,
Jessica A. Kretzmann ,
Gareth L. Nealon ,
Ruhani Singh ,
Tristan D. Clemons ,
Marck Norret ,
Cyrille A. Boyer ,
K. Swaminathan Iyer
,
Sky Edwards ,
Jessica A. Kretzmann ,
Gareth L. Nealon ,
Ruhani Singh ,
Tristan D. Clemons ,
Marck Norret ,
Cyrille A. Boyer ,
K. Swaminathan Iyer
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Abstract
Docetaxel (DTX) is a widely used chemotherapy drug that is associated with numerous side effects and limited bioavailability. We show synthetic copolymer conjugates of docetaxel with drug loading up to 20% and assess their efficacy in MCF-7 cells.