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Royal Society of Chemistry, New Journal of Chemistry, 35(44), p. 14928-14935, 2020

DOI: 10.1039/d0nj00580k

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PLGA-nanoparticles loaded with a thiosemicarbazone derived palladium(ii) complex as a potential agent to new formulations for human ovarian carcinoma treatment

Journal article published in 2020 by Carolina G. Oliveira ORCID, Luciana F. Dalmolin, R. T. C. Silva, Renata F. V. Lopez, Pedro I. S. Maia ORCID, Jéferson A. Moreto ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The encapsulation process of the PdII complex [PdCl(PPh3)(PrCh)], a promising cytotoxic agent on ovarian cancer cells, in PLGA polymer was studied. The cytotoxicity results showed that the formulation led to a significant reduction of the ovarian cell viability (80% at 1 μM).