Published in
Royal Society of Chemistry, Chemical Communications, 57(56), p. 7949-7952, 2020
DOI: 10.1039/d0cc02976a
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Synthesis of protected 3-aminopiperidine and 3-aminoazepane derivatives using enzyme cascades
Journal article published in 2020 by
Grayson J. Ford,
Nico Kress,
Ashley P. Mattey 
,
Lorna J. Hepworth,
Christopher R. Baldwin,
James R. Marshall,
Lisa S. Seibt ,
Min Huang,
William R. Birmingham ,
Nicholas J. Turner ,
Sabine L. Flitsch
,
Lorna J. Hepworth,
Christopher R. Baldwin,
James R. Marshall,
Lisa S. Seibt ,
Min Huang,
William R. Birmingham ,
Nicholas J. Turner ,
Sabine L. Flitsch
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Abstract
Synthesis of Cbz-protected 3-aminopiperidine and 3-aminoazepane using a multi-enzyme cascade consisting of galactose oxidase and imine reductase variants.