Published in
Royal Society of Chemistry, Chemical Communications, 47(56), p. 6420-6423, 2020
DOI: 10.1039/d0cc02321c
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Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action
Journal article published in 2020 by
Nayara Braga Emidio 
,
Hayeon Baik,
David Lee,
René Stürmer,
Jörn Heuer,
Alysha G. Elliott ,
Mark A. T. Blaskovich ,
Katharina Haupenthal,
Nicole Tegtmeyer,
Werner Hoffmann,
Christina I. Schroeder ,
Markus Muttenthaler
,
Hayeon Baik,
David Lee,
René Stürmer,
Jörn Heuer,
Alysha G. Elliott ,
Mark A. T. Blaskovich ,
Katharina Haupenthal,
Nicole Tegtmeyer,
Werner Hoffmann,
Christina I. Schroeder ,
Markus Muttenthaler
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Abstract
Chemical synthesis of gut peptide TFF1 and its homodimer was achieved by a two-fragment ligation strategy followed by oxidative folding.