Published in
Royal Society of Chemistry, Nanoscale, 21(12), p. 11518-11525, 2020
DOI: 10.1039/d0nr01060j
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Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles
Journal article published in 2020 by
Rachael L. Grime 
,
Joelle Goulding ,
Romez Uddin ,
Leigh A. Stoddart ,
Stephen J. Hill ,
David R. Poyner ,
Stephen J. Briddon ,
Mark Wheatley
,
Joelle Goulding ,
Romez Uddin ,
Leigh A. Stoddart ,
Stephen J. Hill ,
David R. Poyner ,
Stephen J. Briddon ,
Mark Wheatley
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Abstract
Combining the technologies of encapsulation of GPCRs in SMA lipid particles with fluorescence correlation spectroscopy provides a versatile characterisation platform.