Arylsulfonyl histamine derivatives as powerful and selective α-glucosidase inhibitors
Journal article published in 2020 by
M. I. Osella,
M. O. Salazar 
,
M. D. Gamarra,
D. M. Moreno ,
F. Lambertucci,
D. E. Frances,
R. L. E. Furlan
,
M. D. Gamarra,
D. M. Moreno ,
F. Lambertucci,
D. E. Frances,
R. L. E. Furlan
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Abstract
Nα,Nτ-Di-4-trifluorobenzenesulfonyl histamine inhibits α-glucosidase in vitro reversibly and selectively with a Ki value of 11.6 μM, and shows an in vivo hypoglycemic effect in mice.