Published in
Royal Society of Chemistry, Polymer Chemistry, 16(11), p. 2791-2798, 2020
DOI: 10.1039/d0py00082e
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Hydrogen-bonded supramolecular micelle-mediated drug delivery enhances the efficacy and safety of cancer chemotherapy
Journal article published in 2020 by
Chih-Chia Cheng 
,
Ya-Ting Sun,
Ai-Wei Lee,
Shan-You Huang,
Wen-Lu Fan,
Yu-Hsuan Chiao ,
Chih-Wei Chiu,
Juin-Yih Lai
,
Ya-Ting Sun,
Ai-Wei Lee,
Shan-You Huang,
Wen-Lu Fan,
Yu-Hsuan Chiao ,
Chih-Wei Chiu,
Juin-Yih Lai
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Abstract
Multiple hydrogen-bonded supramolecular polymers tend to form stable spherical micelles with oppositely charged anticancer drugs in biological environments, which improves cellular drug uptake and more effectively induces apoptosis in cancer cells.