Royal Society of Chemistry, Organic and Biomolecular Chemistry, 15(18), p. 2838-2844, 2020
DOI: 10.1039/d0ob00203h
Full text: Unavailable
Cyclic lipopeptides are often challenging synthetic targets. A synthetic approach is presented that employs cyclisation by intramolecular native chemical ligation (NCL) and a thiol–ene “CLipPA” reaction to afford S-lipidated analogues of iturin A.