Published in
Royal Society of Chemistry, Chemical Communications, 27(56), p. 3915-3918, 2020
DOI: 10.1039/c9cc09887a
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The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNAviaa sequential bi–bi mechanism
Journal article published in 2020 by
Mashael A. Alqasem,
Claire Fergus,
J. Mike Southern 
,
Stephen J. Connon ,
Vincent P. Kelly
,
Stephen J. Connon ,
Vincent P. Kelly
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Abstract
The mechanism of catalysis associated with the human TGT enzyme has been elucidated and differs from that associated with its eubacterial counterpart.