Published in
Royal Society of Chemistry, Biomaterials Science, 1(8), p. 333-341, 2020
DOI: 10.1039/c9bm01766f
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Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma
Journal article published in 2020 by
Roberto Molinaro 
,
Jonathan O. Martinez,
Assaf Zinger,
Alessandro De Vita ,
Gianluca Storci,
Noemi Arrighetti ,
Enrica De Rosa,
Kelly A. Hartman,
Nupur Basu,
Nima Taghipour,
Claudia Corbo ,
Ennio Tasciotti
,
Jonathan O. Martinez,
Assaf Zinger,
Alessandro De Vita ,
Gianluca Storci,
Noemi Arrighetti ,
Enrica De Rosa,
Kelly A. Hartman,
Nupur Basu,
Nima Taghipour,
Claudia Corbo ,
Ennio Tasciotti
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Abstract
Biomimetic nanovesicles deriving from leukocytes membrane proteins, called leukosomes, exhibit increased targeting of cancer vasculature and stroma by exploiting the inflammatory pathway responsible for recruiting immune cells to the cancer lesion.