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Royal Society of Chemistry, Chemical Communications, 99(55), p. 14968-14971, 2019

DOI: 10.1039/c9cc07883e

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Polyamine transport system-targeted nanometric micelles assembled from epipodophyllotoxin-amphiphiles

Journal article published in 2019 by Julien Alliot ORCID, Ioanna Theodorou ORCID, Frédéric Ducongé ORCID, Edmond Gravel ORCID, Eric Doris ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Micelle-forming amphiphilic drug conjugates were synthesized starting from a biologically active epipodophyllotoxin derivative which was covalently inserted in between a hydrophilic targeting spermine unit, and a hydrophobic stearyl chain.