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Nanoscale Advances, 3(1), p. 1002-1012, 2019

DOI: 10.1039/c8na00271a

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Colloidal hydroxyethyl starch for tumor-targeted platinum delivery

Journal article published in 2019 by Chen Xiao, Hang Hu, Hai Yang, Si Li, Hui Zhou, Jian Ruan, Yuting Zhu, Xiangliang Yang ORCID, Zifu Li ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Hydroxyethyl starch (HES) was directly conjugated with cis-platinum prodrugviaan ester bond and decorated with active targeting molecule, lactobionic acid (LA), to afford LA-HES-Pt, which contributes toward higherin vitroantitumor activity against hepatoma carcinoma cells, HepG-2, as compared to cis-platinum.