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American Chemical Society, Journal of Medicinal Chemistry, 13(62), p. 6241-6261, 2019

DOI: 10.1021/acs.jmedchem.9b00525

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(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine (PQR530), a Potent, Orally Bioavailable, and Brain-Penetrable Dual Inhibitor of Class I PI3K and mTOR Kinase

Journal article published in 2019 by Denise Rageot ORCID, Thomas Bohnacker, Erhan Keles, Jacob A. McPhail, Reece M. Hoffmann, Anna Melone, Chiara Borsari ORCID, Rohitha Sriramaratnam, Alexander M. Sele ORCID, Florent Beaufils, Paul Hebeisen, Doriano Fabbro, Petra Hillmann, John E. Burke ORCID, Matthias P. Wymann ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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