Matthias Wymann - Dissemin

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All papers authored by Matthias Wymann

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2022 Chiara Borsari

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, Erhan Keles, Jacob A. McPhail, Alexander Schaefer, Rohitha Sriramaratnam, Wojciech Goch, Thorsten Schaefer, Martina De Pascale

ORCID

ORCID

, Matthias Gstaiger, John E. Burke

ORCID

, Matthias P. Wymann

ORCID

Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα

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2021 Manoj K. Rathinaswamy

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, Zied Gaieb, Kaelin D. Fleming

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, Chiara Borsari

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, Noah J. Harris, Brandon E. Moeller, Matthias P. Wymann

ORCID

, Rommie E. Amaro, John E. Burke

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Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors

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Chiara Borsari

ORCID

ORCID

, Andrea Treyer

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, Martina De Pascale

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, Paul Hebeisen, Matthias Hamburger

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, Matthias P. Wymann

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Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood–brain barrier permeability

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2020 Chiara Borsari

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, Erhan Keles, Denise Rageot, Andrea Treyer

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, Thomas Bohnacker, Lukas Bissegger, Martina De Pascale

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, Anna Melone, Rohitha Sriramaratnam, Florent Beaufils, Matthias Hamburger

ORCID

, Paul Hebeisen, Wolfgang Löscher, Doriano Fabbro, Petra Hillmann and 1 other authors

4-(Difluoromethyl)-5-(4-((3R,5S)-3,5-dimethylmorpholino)-6-((R)-3-methylmorpholino)-1,3,5-triazin-2-yl)pyridin-2-amine (PQR626), a Potent, Orally Available, and Brain-Penetrant mTOR Inhibitor for the Treatment of Neurological Disorders

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