Published in
Royal Society of Chemistry, Biomaterials Science, 10(7), p. 4022-4026, 2019
DOI: 10.1039/c9bm01145e
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Antigen-enabled facile preparation of MOF nanovaccine to activate the complement system for enhanced antigen-mediated immune response
Journal article published in 2019 by
Yanxin Qi,
Lei Wang 
,
Huanhuan Guo,
Yong Pan,
Zhigang Xie ,
Ningyi Jin,
Yubin Huang
,
Huanhuan Guo,
Yong Pan,
Zhigang Xie ,
Ningyi Jin,
Yubin Huang
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Abstract
Since current subunit vaccines are limited by a short halflife in vivo and weak immune responses when used alone without adjuvants, there is an unmet need for combing carriers with complement activation signals to interrupt outbreaks in real-time.