Published in
Royal Society of Chemistry, Soft Matter, 36(15), p. 7211-7218, 2019
DOI: 10.1039/c9sm00371a
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Deciphering multivalent glycocluster–lectin interactions through AFM characterization of the self-assembled nanostructures
Journal article published in 2019 by
Francesca Zuttion 
,
Delphine Sicard,
Lucie Dupin,
Gérard Vergoten,
Camille Girard-Bock ,
Mimouna Madaoui,
Yann Chevolot ,
Francois Morvan ,
Sébastien Vidal ,
Jean-Jacques Vasseur ,
Eliane Souteyrand,
Magali Phaner-Goutorbe
,
Delphine Sicard,
Lucie Dupin,
Gérard Vergoten,
Camille Girard-Bock ,
Mimouna Madaoui,
Yann Chevolot ,
Francois Morvan ,
Sébastien Vidal ,
Jean-Jacques Vasseur ,
Eliane Souteyrand,
Magali Phaner-Goutorbe
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Abstract
Arrangements formed by the lectin LecA and five different synthetic glycoclusters were studied by AFM imaging combined to MD simulations. Arrangements and affinities differ depending on the nature of the core and the branches of the glycoclusters.