Published in

Royal Society of Chemistry, Organic and Biomolecular Chemistry, 28(17), p. 6748-6752, 2019

DOI: 10.1039/c9ob01209e

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A chemical approach for the synthesis of the DNA-binding domain of the oncoprotein MYC

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We describe the first chemical synthesis of a functional mutant of the DNA binding domain of the oncoprotein MYC, using two alternative strategies which involve either one or two Native Chemical Ligations (NCLs).