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Royal Society of Chemistry, Chemical Communications, 55(55), p. 7914-7917, 2019

DOI: 10.1039/c9cc04022f

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Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides

Journal article published in 2019 by Jiraborrirak Charoenpattarapreeda ORCID, Yaw Sing Tan, Jessica Iegre ORCID, Stephen J. Walsh ORCID, Elaine Fowler ORCID, Rohan S. Eapen ORCID, Yuteng Wu, Hannah F. Sore ORCID, Chandra S. Verma ORCID, Laura Itzhaki ORCID, David R. Spring ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

An electrophile-bearing linker was developed for the generation of a stapled peptide covalent inhibitor of MDM2 via a two-component CuAAC peptide stapling.