Published in
Inorganic Chemistry Frontiers, 4(7), p. 859-870, 2020
DOI: 10.1039/c9qi01172b
Links
Tools
Light-induced disruption of an acyl hydrazone link as a novel strategy for drug release and activation: isoniazid as a proof-of-concept case
Journal article published in 2020 by
Edinaira Deodato Nunes,
Anne Drumond Villela,
Luiz Augusto Basso 
,
Edson H. Teixeira ,
Alexandre L. Andrade,
Mayron A. Vasconcelos ,
Luiz G. do Nascimento Neto ,
Ana C. S. Gondim ,
Izaura C. N. Diógenes ,
Adolfo I. B. Romo ,
Otaciro R. Nascimento ,
Davila Zampieri ,
Tércio Freitas Paulo ,
Idalina Maria Moreira de Carvalho ,
Luiz Gonzaga de França Lopes
and other authors.
,
Edson H. Teixeira ,
Alexandre L. Andrade,
Mayron A. Vasconcelos ,
Luiz G. do Nascimento Neto ,
Ana C. S. Gondim ,
Izaura C. N. Diógenes ,
Adolfo I. B. Romo ,
Otaciro R. Nascimento ,
Davila Zampieri ,
Tércio Freitas Paulo ,
Idalina Maria Moreira de Carvalho ,
Luiz Gonzaga de França Lopes
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
Published version:
archiving forbidden
Data provided by 
Abstract
Photocleavage of an acyl hydrazone bridge was achieved by conjugating isoniazid to a ruthenium(ii) metal complex through the generation of singlet oxygen, which released and activated the anti-tuberculosis pro-drug isoniazid.