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Royal Society of Chemistry, Chemical Communications, 31(55), p. 4483-4486, 2019

DOI: 10.1039/c9cc01067j

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Probing transient non-native states in amyloid beta fiber elongation by NMR

Journal article published in 2019 by Jeffrey R. Brender ORCID, Anirban Ghosh, Samuel A. Kotler, Janarthanan Krishnamoorthy, Swapna Bera, Vanessa Morris ORCID, Timir Baran Sil, Kanchan Garai, Bernd Reif ORCID, Anirban Bhunia ORCID, Ayyalusamy Ramamoorthy ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Using NMR to probe transient binding of Aβ1–40 monomers to fibers, we find partially bound conformations with the highest degree of interaction near F19–K28 and a lesser degree of interaction near the C-terminus (L34–G37).