Published in
Royal Society of Chemistry, MedChemComm, 3(10), p. 431-438, 2019
DOI: 10.1039/c8md00593a
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2,2-Dimethyl-3,4-dihydro-2H-1,4-benzoxazines as isosteres of 2,2-dimethylchromans acting as inhibitors of insulin release and vascular smooth muscle relaxants
Journal article published in 2019 by
Bernard Pirotte 
,
Xavier Florence,
Eric Goffin,
Philippe Lebrun
,
Xavier Florence,
Eric Goffin,
Philippe Lebrun
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Abstract
The present study describes the synthesis and biological evaluation of 4-phenylureido/thioureido-substituted 2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazines as isosteres of corresponding 2,2-dimethylchromans reported as KATP channel openers.