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Royal Society of Chemistry, Organic and Biomolecular Chemistry, 47(16), p. 9171-9184, 2018

DOI: 10.1039/c8ob02609b

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Syntheses and in vitro biological evaluation of S1PR1 ligands and PET studies of four F-18 labeled radiotracers in the brain of nonhuman primates

Journal article published in 2018 by Zonghua Luo ORCID, Junbin Han, Hui Liu ORCID, Adam J. Rosenberg ORCID, Delphine L. Chen, Robert J. Gropler, Joel S. Perlmutter ORCID, Zhude Tu ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Four potent and selective F-18 labeled S1PR1 radiotracers were radiosynthesized and three of them were able to cross blood–brain-barrier and enter into the brain of nonhuman primates.