Published in

Royal Society of Chemistry, Physical Chemistry Chemical Physics, 46(20), p. 29314-29324, 2018

DOI: 10.1039/c8cp04059a

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A molecular dynamics model for glycosylphosphatidyl-inositol anchors: “flop down” or “lollipop”?

Journal article published in 2018 by Pallavi Banerjee, Marko Wehle, Reinhard Lipowsky ORCID, Mark Santer ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Computational model for GPI anchors tested in DMPC and POPC bilayers. The free anchor rarely occurs as an erected “lollipop-like” conformation, it rather “flops down” onto the bilayer surface. Yet an attached protein (here green fluorescent protein) exhibits extensive orientational flexibility due to the phospho-ethanolamine linker.