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Royal Society of Chemistry, Chemical Communications, 90(54), p. 12738-12741, 2018

DOI: 10.1039/c8cc06725b

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From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom

Journal article published in 2018 by Cristina Díaz-Perlas ORCID, Monica Varese ORCID, Salvador Guardiola, Jesús García ORCID, Macarena Sánchez-Navarro ORCID, Ernest Giralt ORCID, Meritxell Teixidó ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

A monocyclic peptidomimetic version of chlorotoxin, MiniCTX3, was developed as a BBB-shuttle being able to transport nanoparticles across endothelial cells. Our results reveal animal venoms as an outstanding source of BBB-shuttles.