Flavonoids induce cell death in Leishmania amazonensis: in vitro characterization by flow cytometry and Raman spectroscopy
Journal article published in 2019 by
Morgana V. Araújo,
Aline C. Queiroz 
,
João F. M. Silva,
Amanda E. Silva,
João K. S. Silva,
Girliane R. Silva,
Elaine C. O. Silva,
Samuel T. Souza ,
Eduardo J. S. Fonseca ,
Celso A. Camara ,
Tania M. S. Silva ,
Magna S. Alexandre-Moreira
,
João F. M. Silva,
Amanda E. Silva,
João K. S. Silva,
Girliane R. Silva,
Elaine C. O. Silva,
Samuel T. Souza ,
Eduardo J. S. Fonseca ,
Celso A. Camara ,
Tania M. S. Silva ,
Magna S. Alexandre-Moreira
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Abstract
The present study investigated gossypetin 3,7,8,4′-tetra-O-methyl ether (1) and kaempferol 3,7-di-O-methyl ether (3) which showed significant leishmanicidal activity without toxic effects to host cells.