Published in
Royal Society of Chemistry, Chemical Communications
DOI: 10.1039/c8cc05831h
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Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials
Journal article published in 2018 by
N. L. Fletcher 
,
Z. H. Houston ,
J. D. Simpson ,
R. N. Veedu ,
K. J. Thurecht
,
Z. H. Houston ,
J. D. Simpson ,
R. N. Veedu ,
K. J. Thurecht
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Abstract
We report a novel multifunctional hyperbranched polymer based on polyethylene glycol (PEG) as a nanomedicine platform that facilitates longitudinal and quantitative 89Zr-PET imaging, enhancing knowledge of nanomaterial biodistribution and pharmacokinetics/pharmacodynamics both in vivo and ex vivo.