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Royal Society of Chemistry, Chemical Communications

DOI: 10.1039/c8cc05831h

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Designed multifunctional polymeric nanomedicines: long-term biodistribution and tumour accumulation of aptamer-targeted nanomaterials

Journal article published in 2018 by N. L. Fletcher ORCID, Z. H. Houston ORCID, J. D. Simpson ORCID, R. N. Veedu ORCID, K. J. Thurecht ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We report a novel multifunctional hyperbranched polymer based on polyethylene glycol (PEG) as a nanomedicine platform that facilitates longitudinal and quantitative 89Zr-PET imaging, enhancing knowledge of nanomaterial biodistribution and pharmacokinetics/pharmacodynamics both in vivo and ex vivo.