Published in
Royal Society of Chemistry, Chemical Communications, 62(54), p. 8637-8640
DOI: 10.1039/c8cc03446j
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Structural differences between toxic and nontoxic HypF-N oligomers
Journal article published in 2018 by
Claudia Capitini,
Jayneil R. Patel,
Antonino Natalello 
,
Cristiano D’Andrea,
Annalisa Relini,
James A. Jarvis,
Leila Birolo,
Alessia Peduzzo ,
Michele Vendruscolo,
Paolo Matteini ,
Christopher M. Dobson,
Alfonso De Simone,
Fabrizio Chiti
,
Cristiano D’Andrea,
Annalisa Relini,
James A. Jarvis,
Leila Birolo,
Alessia Peduzzo ,
Michele Vendruscolo,
Paolo Matteini ,
Christopher M. Dobson,
Alfonso De Simone,
Fabrizio Chiti
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Abstract
We have studied two misfolded oligomeric forms of the protein HypF-N, which show similar morphologies but very different toxicities.