Published in
Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 30(6), p. 4903-4908
DOI: 10.1039/c8tb01070f
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A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging
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Abstract
Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.