Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 14(15), p. 2947-2952, 2017
DOI: 10.1039/c7ob00220c
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Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis
Journal article published in 2017 by
Maurício Morais 
,
João P. M. Nunes,
Kersti Karu,
Nafsika Forte,
Irene Benni,
Mark E. B. Smith,
Stephen Caddick,
Vijay Chudasama ,
James R. Baker
,
João P. M. Nunes,
Kersti Karu,
Nafsika Forte,
Irene Benni,
Mark E. B. Smith,
Stephen Caddick,
Vijay Chudasama ,
James R. Baker
This paper is made freely available by the publisher.
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Abstract
Dibromomaleimide (DBM) reagents are described which hydrolyse rapidly post-conjugation, representing an optimised platform for homogeneous and stable antibody conjugation.