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Royal Society of Chemistry, Organic Chemistry Frontiers, 14(5), p. 2171-2178, 2018

DOI: 10.1039/c8qo00429c

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Searching for original natural products by molecular networking: detection, isolation and total synthesis of chloroaustralasines

Journal article published in 2018 by F. Olivon ORCID, C. Apel ORCID, P. Retailleau ORCID, P. M. Allard ORCID, J. L. Wolfender ORCID, D. Touboul ORCID, F. Roussi ORCID, M. Litaudon ORCID, S. Desrat ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Four unprecedented chlorinated monoterpenyl quinolones have been isolated using a molecular networking based prioritisation strategy. The bio-inspired total synthesis of chloroaustralasine A involving a chloroperoxydase-mediated hydroxychlorination is described.