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Royal Society of Chemistry, Chemical Communications, 97(52), p. 14031-14034
DOI: 10.1039/c6cc08356k
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Intramolecular radical non-reductive alkylation of ketones via transient enamines
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Abstract
A five-minute one-pot cyclization of dichloro-acetamide-tethered ketones was achieved under microwave activation through a radical procedure involving a transient enamine.