Published in
Royal Society of Chemistry, MedChemComm, 6(9), p. 995-1010
DOI: 10.1039/c8md00095f
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Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines
Journal article published in 2018 by
Itamar Luís Gonçalves 
,
Liliana Rockenbach,
Gustavo Machado das Neves,
Gabriela Göethel,
Fabiana Nascimento,
Luciano Porto Kagami,
Fabrício Figueiró ,
Gabriel Oliveira de Azambuja,
Amanda de Fraga Dias,
Andressa Amaro,
Lauro Mera de Souza ,
Ivan da Rocha Pitta,
Daiana Silva Avila,
Daniel Fábio Kawano,
Solange Cristina Garcia
and other authors.
,
Liliana Rockenbach,
Gustavo Machado das Neves,
Gabriela Göethel,
Fabiana Nascimento,
Luciano Porto Kagami,
Fabrício Figueiró ,
Gabriel Oliveira de Azambuja,
Amanda de Fraga Dias,
Andressa Amaro,
Lauro Mera de Souza ,
Ivan da Rocha Pitta,
Daiana Silva Avila,
Daniel Fábio Kawano,
Solange Cristina Garcia
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
An original and focused library of dihydropyrimidin-2-thiones N-1 aryl substituted derived from monastrol was designed and synthesized in order to discover a more effective Eg5 ligand.