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Royal Society of Chemistry, Catalysis Science & Technology, 19(6), p. 7172-7185, 2016

DOI: 10.1039/c6cy00356g

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QM/MM study of the mechanism of reduction of 3-hydroxy-3-methylglutaryl coenzyme A catalyzed by human HMG-CoA reductase

Journal article published in 2016 by Eduardo F. Oliveira, Nuno M. F. S. A. Cerqueira ORCID, Maria J. Ramos, Pedro A. Fernandes
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Detailing with atomistic resolution the reaction mechanism of human HMG-CoA reductase (HMG-CoA-R) might provide valuable insights for the development of new cholesterol-lowering drugs.