Published in
Royal Society of Chemistry, Dalton Transactions, 41(46), p. 14174-14185
DOI: 10.1039/c7dt02928d
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An unsymmetric cisplatin-based Pt(iv) derivative containing 2-(2-propynyl)octanoate: a very efficient multi-action antitumor prodrug candidate
Journal article published in 2017 by
Elisabetta Gabano 
,
Mauro Ravera ,
Ilaria Zanellato ,
Stefano Tinello,
Andrea Gallina ,
Beatrice Rangone ,
Valentina Gandin ,
Cristina Marzano ,
Maria Grazia Bottone ,
Domenico Osella
,
Mauro Ravera ,
Ilaria Zanellato ,
Stefano Tinello,
Andrea Gallina ,
Beatrice Rangone ,
Valentina Gandin ,
Cristina Marzano ,
Maria Grazia Bottone ,
Domenico Osella
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Abstract
The assembly of cisplatin and the histone deacetylase inhibitor 2-(2-propynyl)octanoate affords a Pt(iv) multi-action anticancer prodrug.