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Royal Society of Chemistry, Organic and Biomolecular Chemistry, 37(15), p. 7956-7976

DOI: 10.1039/c7ob02045g

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Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL

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This paper is available in a repository.

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Abstract

Anti-apoptotic proteins, like the Bcl-2 family proteins, present an important therapeutic cancer drug target.