Royal Society of Chemistry, Nanoscale, 1(5), p. 143-146, 2013
DOI: 10.1039/c2nr31877f
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We investigated the penetration and thermotherapy efficiency of different surface coated gold nanorods (Au NRs) in multicellular tumor spheroids. The current data show that negatively charged Au NRs, other than positively charged Au NRs, can penetrate deep into the tumor spheroids and achieve a significant thermal therapeutic benefit.