Published in
Royal Society of Chemistry, Organic Chemistry Frontiers, 4(5), p. 531-538
DOI: 10.1039/c7qo01006k
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Ball-milling and cheap reagents breathe green life into the one hundred-year-old Hofmann reaction
Journal article published in 2018 by
Rita Mocci 
,
Sergio Murgia ,
Lidia De Luca,
Evelina Colacino ,
Francesco Delogu,
Andrea Porcheddu
,
Sergio Murgia ,
Lidia De Luca,
Evelina Colacino ,
Francesco Delogu,
Andrea Porcheddu
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Abstract
A very efficient mechanically activated synthesis of isocyanides directly from primary amines and without extra-solvent addition has been reported.