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Royal Society of Chemistry, RSC Advances, 85(7), p. 53658-53666, 2017

DOI: 10.1039/c7ra08588e

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Cyanocobalamin conjugates of cisplatin and diaminocyclohexane-platinum(ii): matrix-assisted laser desorption ionization mass spectrometry characterization using 4-chloro-α-cyanocinnamic acid as the matrix

Journal article published in 2017 by G. Ventura, F. Arnesano ORCID, C. D. Calvano ORCID, F. Palmisano, T. R. I. Cataldi ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

cis-Diamminedichloroplatinum(ii), also known as cisplatin, is a widely used chemotherapeutic agent to treat several malignant tumours, but unfortunately it causes serious side effects, especially nausea, vomiting and nephrotoxicity.