Reinhard Lührmann
0000-0003-3253-7518
6 papers found
Refreshing results…
Structural insights into the cross-exon to cross-intron spliceosome switch
PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects
Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins
Structural insights into how Prp5 proofreads the pre-mRNA branch site
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation
Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation
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