Irene Gil-Farina - Dissemin

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All papers authored by Irene Gil-Farina

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2024 Paul Batty

ORCID

ORCID

, Matteo Franco

ORCID

, Choong-Ryoul Sihn, Laura L. Swystun

ORCID

, Saira Afzal, Lorianne Harpell, David Hurlbut, Abbey Pender, Cheng Su, Hauke Thomsen, Christopher Wilson, Loubna Youssar

ORCID

, Andrew Winterborn, Irene Gil-Farina

ORCID

and 1 other authors

Vector integration and fate in the hemophilia dog liver multiple years after AAV-FVIII gene transfer

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2023 Nerea Zabaleta

ORCID

, Irene Gil-Farina

ORCID

Tracing the fate of AAV vectors in the body

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Maria Carmina Castiello, Martina Di Verniere, Elena Draghici, Elena Fontana, Sara Penna, Lucia Sereni, Alessandra Zecchillo, Denise Minuta, Paolo Uva, Marco Zahn, Irene Gil-Farina

ORCID

, Andrea Annoni, Silvia Iaia, Lisa M. Ott de Bruin, Luigi D. Notarangelo and 4 other authors

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations

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2022 Denise E. Sabatino

ORCID

, Frederic D. Bushman, Randy J. Chandler, Ronald G. Crystal, Beverly L. Davidson, Ricardo Dolmetsch, Kevin C. Eggan, Guangping Gao, Irene Gil-Farina

ORCID

, Mark A. Kay, Douglas M. McCarty, Eugenio Montini, Adora Ndu, Jing Yuan

Evaluating the state of the science for adeno-associated virus integration: An integrated perspective

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Saqlain Suleman, Annette Payne

ORCID

, Johnathan Bowden, Sharmin Al Haque, Marco Zahn, Serena Fawaz, Mohammad S. Khalifa, Susan Jobling, David Hay, Matteo Franco, Raffaele Fronza, Wei Wang, Olga Strobel-Freidekind, Annette Deichmann, Yasuhiro Takeuchi and 4 other authors

HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival

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2021 Selcen Öztürk

ORCID

, Yashna Paul, Saira Afzal

ORCID

, Irene Gil-Farina

ORCID

, Anna Jauch, Peter-Martin Bruch

ORCID

, Verena Kalter, Bola Hanna, Lavinia Arseni, Philipp M. Roessner

ORCID

, Manfred Schmidt, Stephan Stilgenbauer, Sascha Dietrich

ORCID

, Peter Lichter

ORCID

ORCID

and 1 other authors

Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients

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2020 Estefania Rodriguez-Garcia

ORCID

, Nerea Zabaleta, Irene Gil-Farina

ORCID

, Manuela Gonzalez-Aparicio

ORCID

, Maite Echeverz

ORCID

, Heike Bähre, Cristina Solano

ORCID

, Iñigo Lasa, Gloria Gonzalez-Aseguinolaza

ORCID

ORCID

AdrA as a Potential Immunomodulatory Candidate for STING-Mediated Antiviral Therapy That Required Both Type I IFN and TNF-α Production

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Peter Horak

ORCID

, Sebastian Uhrig, Maximilian Witzel, Irene Gil-Farina

ORCID

, Barbara Hutter

ORCID

, Tim Rath, Laura Gieldon, Gnana Prakash Balasubramanian, Xavier Pastor, Christoph E. Heilig

ORCID

, Daniela Richter, Evelin Schröck, Claudia R. Ball, Benedikt Brors

ORCID

, Christian J. Braun

ORCID

and 7 other authors

Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia

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2018 Jerry K. Y. Chan, Irene Gil-Farina

ORCID

, Nuryanti Johana, Cecilia Rosales, Yi Wan Tan, Jessika Ceiler, Jenny Mcintosh, Bryan Ogden, Simon N. Waddington, Manfred Schmidt, Arijit Biswas, Mahesh Choolani, Amit C. Nathwani, Citra N. Z. Mattar

Therapeutic expression of human clotting factors IX and X following adeno-associated viral vector–mediated intrauterine gene transfer in early-gestation fetal macaques

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Peer Wünsche, Elias S. P. Eckert, Tim Holland-Letz, Anna Paruzynski, Agnes Hotz-Wagenblatt, Raffaele Fronza, Tim Rath, Irene Gil-Farina

ORCID

, Manfred Schmidt, Christof von Kalle, Christoph Klein, Claudia R. Ball, Friederike Herbst, Hanno Glimm

Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs

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2017 Simone J. Scholz, Raffaele Fronza, Cynthia C. Bartholomä, Daniela Cesana, Eugenio Montini, Christof von Kalle, Irene Gil-Farina

ORCID

, Manfred Schmidt

Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation

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Saira Afzal, Irene Gil-Farina

ORCID

, Richard Gabriel, Shahzad Ahmad

ORCID

, Christof von Kalle, Manfred Schmidt, Raffaele Fronza

Systematic comparative study of computational methods for T-cell receptor sequencing data analysis

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Citra N. Z. Mattar, Irene Gil-Farina

ORCID

, Cecilia Rosales, Nuryanti Johana, Yvonne Yi Wan Tan, Jenny McIntosh, Christine Kaeppel, Simon N. Waddington, Arijit Biswas, Mahesh Choolani, Manfred Schmidt, Amit C. Nathwani, Jerry K. Y. Chan

In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model

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2016 Irene Gil-Farina

ORCID

, Manfred Schmidt

Interaction of vectors and parental viruses with the host genome

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Delia D’Avola, Esperanza López-Franco, Bruno Sangro

ORCID

, Astrid Pañeda, Nadina Grossios, Irene Gil-Farina

ORCID

, Alberto Benito, Jaap Twisk, María Paz, Juan Ruiz, Manfred Schmidt, Harald Petry, Pauline Harper, Rafael Enríquez de Salamanca, Antonio Fontanellas and 2 other authors

Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria

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Irene Gil-Farina

ORCID

, Marianna Di Scala

ORCID

, Eduardo Salido

ORCID

, Esperanza López-Franco

ORCID

, Estefania Rodríguez-García, Mercedes Blasi, Juana Merino, Rafael Aldabe

ORCID

, Jesús Prieto, Gloria Gonzalez-Aseguinolaza

ORCID

Transient Expression of Transgenic IL-12 in Mouse Liver Triggers Unremitting Inflammation Mimicking Human Autoimmune Hepatitis

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Marianna Di Scala, Itziar Otano, Irene Gil-Fariña

ORCID

, Lucia Vanrell, Mirja Hommel, Cristina Olagüe, Africa Vales, Miguel Galarraga, Laura Guembe, Carlos Ortiz de Solorzano, Indrajit Ghosh, Mala K. Maini, Jesús Prieto, Gloria González-Aseguinolaza

Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice

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Marianna Di Scala, Marianna Di Scala, Irene Gil-Fariña

ORCID

, Cristina Olagüe, Africa Vales, Luciano Sobrevals, Puri Fortes

ORCID

, David Corbacho, Gloria González-Aseguinolaza

Identification of IFN-γ-producing T cells as the main mediators of the side effects associated to mouse interleukin-15 sustained exposure

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Irene Gil-Farina

ORCID

, Raffaele Fronza, Christine Kaeppel, Esperanza Lopez-Franco, Valerie Ferreira, Delia D'Avola, Alberto Benito, Jesus Prieto, Harald Petry, Gloria Gonzalez-Aseguinolaza, Manfred Schmidt

Recombinant AAV Integration Is Not Associated With Hepatic Genotoxicity in Nonhuman Primates and Patients

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Manfred Schmidt, Irene Gil-Farina

ORCID

, Hildegard Büning

Reply to “Wild-type AAV Insertions in Hepatocellular Carcinoma Do Not Inform Debate Over Genotoxicity Risk of Vectorized AAV”

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