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All papers authored by Xu Liu

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2022 Filipp Frank, Meredith M. Keen, Anuradha Rao, Leda Bassit, Xu Liu

ORCID

, Heather B. Bowers, Anamika B. Patel, Michael L. Cato, Julie A. Sullivan, Morgan Greenleaf, Anne Piantadosi, Wilbur A. Lam, William H. Hudson, Eric A. Ortlund

Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests

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2021 Filipp Frank, Eric A. Ortlund, Xu Liu

ORCID

Structural insights into glucocorticoid receptor function

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Xu Liu

ORCID

, Emily R. Weikum, Desiree Tilo

ORCID

, Charles Vinson, Eric A. Ortlund

ORCID

Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element

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Filipp Frank

ORCID

, Xu Liu

ORCID

, Eric A. Ortlund

ORCID

Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation

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2020 Suzanne G. Mays, Józef Stec, Xu Liu

ORCID

, Emma H. D’Agostino, Richard J. Whitby, Eric A. Ortlund

Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist

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Xu Liu

ORCID

, Yashuo Wang, Jennifer S. Gutierrez

ORCID

, Jesse M. Damsker, Kanneboyina Nagaraju

ORCID

, Eric P. Hoffman

ORCID

, Eric A. Ortlund

ORCID

Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment

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Alexandra A. Wolfarth

ORCID

, Xu Liu

ORCID

, Trevor M. Darby

ORCID

, Darra J. Boyer, Jocelyn B. Spizman, Joshua A. Owens

ORCID

, Bindu Chandrasekharan, Crystal R. Naudin, Krisztina Z. Hanley, Brian S. Robinson, Eric A. Ortlund

ORCID

, Rheinallt M. Jones

ORCID

, Andrew S. Neish

Proline rich acidic protein-1 (PRAP1) protects the gastrointestinal epithelium from irradiation-induced apoptosis

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2019 Xu Liu

ORCID

, Yashuo Wang, Eric A. Ortlund

ORCID

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthetic Glucocorticoids

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Xu Liu

ORCID

, Lisa C. Golden, Josue A. Lopez, Tyson R. Shepherd, Liping Yu, Ernesto J. Fuentes

Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

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Xu Liu

ORCID

, Ernesto J. Fuentes

Emerging Themes in PDZ Domain Signaling

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2018 John R. Horton, Clayton B. Woodcock, Qin Chen, Xu Liu

ORCID

, Xing Zhang, John Shanks, Ganesha Rai

ORCID

, Bryan T. Mott, Daniel J. Jansen, Stephen C. Kales, Mark J. Henderson, Matthew Cyr, Katherine Pohida, Xin Hu, Pranav Shah and 8 other authors

Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A

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Emily R. Weikum, Xu Liu

ORCID

, Eric A. Ortlund

ORCID

The nuclear receptor superfamily: A structural perspective

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John R. Horton, Horton Jr, Xu Liu

ORCID

, Lizhen Wu, Kai Zhang, John Shanks, Xing Zhang, Ganesha Rai

ORCID

, Bryan T. Mott, Daniel J. Jansen, Stephen C. Kales, Mott Bt, Mark J. Henderson, Jansen Dj, Kales Sc and 13 other authors

Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A

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2017 Guo Chen, Jianxiang Chen, Yiting Qiao, Yaru Shi, Wei Liu, Qi Zeng, Hui Xie, Xiaorui Shi, Youwei Sun, Xu Liu

ORCID

, Tongyu Li, Liqian Zhou, Jianqin Wan, Tian Xie, Hangxiang Wang and 1 other authors

ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair

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2016 Xu Liu

ORCID

, David C. Speckhard, Tyson R. Shepherd, Young Joo Sun, Sarah R. Hengel, Liping Yu, C. Andrew Fowler, Lokesh Gakhar, Ernesto J. Fuentes

Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions

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John R. Horton, Horton Jr, Xu Liu

ORCID

, Molly Gale, Lizhen Wu, John R. Shanks, Shanks Jr, Xing Zhang, Philip J. Webber, Joshua S. K. Bell, Stephen C. Kales, Webber Pj, Bryan T. Mott, Bell Jsk, Kales Sc and 18 other authors

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds

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2015 John R. Horton, Horton Jr, Amanda Engstrom, Elizabeth L. Zoeller, Zoeller El, Xu Liu

ORCID

, Shanks Jr, John R. Shanks, Xing Zhang, Margaret A. Johns, Johns Ma, Vertino Pm, Paula M. Vertino, Haian Fu, Xiaodong Cheng

Characterization of a linked Jumonji domain of the KDM5/JARID1 family of histone H3 lysine 4 demethylases

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2013 Xu Liu

ORCID

, Tyson R Shepherd, Ann M Murray, Zhen Xu, Ernesto J Fuentes

The Structure of the Tiam1 PDZ Domain/ Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics

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2010 Tyson R. Shepherd, Suzi M. Klaus, Xu Liu

ORCID

ORCID

, Kris A. DeMali, Ernesto J. Fuentes

The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion

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